Well, the last Grand Duke of Tuscany of House of Medici, Cosimo III, had only one daughter. She was named Anna Maria Luisa de'Medici (b. 1667, d. 1743), and she married Duke Johann Wilhelm of Palatinate-Neuburg. House of Medici extinguished in XVIII century, just like all of its collateral branches.
However there could still be someone who's very distantly related to them among European Houses...who knows...
2j) Cosimo III, Gr Duke of Tuscany (14 Aug 1642-31 Oct 1723); m.20 Jun 1661 (div 1675) Marguerite Louise d'Orléans (1645-1721)
1k) Ferdinando (9 Aug 1663-31 Oct 1713); m.19 Jan 1689 Violante of Bavaria (1673-1731)
2k) Gian Gastone, Gr Duke of Tuscany (24 May 1671-9 Jul 1737); m.2 Jul 1697 Anna Marie Franziska of Saxe-Lauenburg (1672-1741)
3k) Anna Maria (11 Aug 1667-18 Feb 1743); m.5 Jun 1691 Johann Wilhelm Kfst von der Pfalz (1658-1716)