One of the reasons I first became interested in the Romanovs was due to the mystery of Anastasia. I read as much as possible about the subject, and for some time I was 50/50 re: whether she had survived or not.
I happen to think photos of Anna Anderson Manahan do, on occasion, bear resembalance to the young Anastasia and/or her relatives. I'm also taking into consideration that people can age to the point that they hardly resemble who they once were.
However, I do respect the DNA test. I am very certain, from what I have read and also observed in documentaries, that the bones now resting at Peter and Paul Fortress are those of the prisoners at Ekaterinberg. As for what happened to the bodies of Alexei and Marie or Anastasia . . . good question.
In short, while I am almost completely convinced that Mrs. Manahan was not Anastasia, it will be interesting to "stand by" for additional discoveries and tests.