When Alessandro of Medici, illegitimate son of Giulio of Medici (later Pope Clement VII) and his lover Simonetta da Collevechio (a black serving-woman), was assasinated by his distant cousin Lorenzino di Medici in 1537, the power came to another distant cousin, Cosimo of Medici. Cosimo ruled as grand duke Cosimo I of Tuscany from 1537 to 1574.
Cosimo married in 1539 Eleonora di Toledo, a rich heiress as daughter of the spanish viceroy of Naples Pedro Alvarez de Toledo. The couple Cosimo & Eleonora had eleven children, but Eleonora died with two of the sons when they suffered an attack of malaria while traveling to Pisa in 1562. Cosimo married again, this time with his mistress Camilla Martelli. Camilla offered him three children before her death, in 1574.
The eldest male son of Cosimo by his first wife Eleonore was named Francesco. He was to rule after the father. On december 18, 1565 Francesco married Johanna of Austria, a daughter of the german emperor Ferdinand I and his wife Anna, queen of Bohemia and Hungary.
These are portraits of Francesco and Johanna:
These are portraits of Cosimo and Eleonora, father and mother of Francesco:
And these are portraits of emperor Ferdinand and queen Anna, father and mother of Johanna:
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Francesco and Johanna were not a happy couple. The calm, gentle and plain Johanna was homesick for her natal Austria, and Francesco was not a charming husband, neither a faithful husband, to her. But they had seven children, six daughters and only a son. The daughters were Eleonore, Romola, Anna, Isabella, Lucrezia and Maria. The son was named Filippo.
After the death of Johanna in 1578, aged thirty, it was said that she has been poisoned by her husband Francesco, who became grand duke in suceeding his father Cosimo in 1574, and the mistress of Francesco, Bianca Capello, named the enchantress of Venetia. This is a portrait that shows the beauty of Bianca Capello: