Isabel was very much in love with Felipe, she just adored him. In 1565, when she met her mother and her brothers in Bayonne, her mother said to her: "You act in a very Spanish manner" Isabel answered: "Because I am Spanish, but I am still the daughter that left France five years ago".
She also loved dearly her daughters, with whom she played dayly, unlike many queens of the Renaissance. Her daughters also must have loved her very much: when Isabel died in 1568, Isabel Clara Eugenia was only two years old. However, when in 1570 Felipe remarried his niece Anna of Austria, the infantas were told by their governess that their mother had returned from Heaven. When Anna appeared, Catalina quickly embraced her. But Isabel Clara Eugenia, very seriously said: "This is not my mother, my mother was dark-haried and this woman is blonde!" After hearing this, Anna said to Isabel Clara: "That is true, darling, I am not your mother, but I will love you as if I were". And she did...